BIGG

The role of mathematical modelling in the development of recommendations in the 2013 WHO consolidated antiretroviral therapy guidelines

Easterbrook, PJ; Doherty, MC; Perriëns, JH; Barcarolo, JL; Hirnschall, GO.

AIDS; 28 (Suppl 1), 2014

Despite the exponential growth in the literature on modelling and simulation studies of impact and cost-effectiveness in different aspects of healthcare, there is no clear consensus on the appropriate role of modelling in the development of recommendations in clinical guidelines. This is compounded both ...

Terapia Antirretroviral Altamente Activa, Infecciones por VIH, Política de Salud, Modelos Teóricos, Infecciones por VIH/diagnóstico, Infecciones por VIH/tratamiento farmacológico, Terapia Antirretroviral Altamente Activa/normas

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Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) of Pneumococcal Vaccines for Immunocompromised Children Aged 6 through 18 Years

GRADE was used to evaluate 13-valent Pneumococcal Conjugate Vaccine (PCV13) for routine use among immunocompromised children aged 6 through 18 years. Evidence of benefits, harms, values and preferences, and cost-effectiveness were reviewed in accordance with GRADE methods.[1] The primary policy question...